Researchers at Karolinska Institutet in Sweden and the RIKEN Center for Brain Science in Japan have identified two receptors ...

Bicara completed its Initial Public Offering ("IPO") on September 16th, 2024, raising ~$362m via the issuance of ~20.13m ...

Now Vijayanand and his colleagues have discovered the cellular driver that leads to T RM cell development. Their findings, ...

In their new study, the LJI scientists are the first to show that GPR25 is induced by a signaling molecule called TGF-β.

Chemerin is a key adipokine that regulates lipid metabolism and insulin sensitivity, and thus is involved in many metabolic ...

UNC researchers discovered how a key step in cell signaling works by showing exactly how G proteins detach from receptors ...

Scientists at the University of North Carolina School of Medicine have made a breakthrough in understanding how cells respond ...

Chemerin is a key adipokine that regulates lipid metabolism and insulin sensitivity, and thus is involved in many metabolic diseases such as obesity ...

New research, led by LJI scientists, offers a potential way to boost tissue-resident memory T cell numbers to better fight disease.

GPCRs (G protein-coupled receptors), also known as 7 transmembrane domain receptors, are the largest receptor family in the human genome, with ≈800 members. GPCRs regulate nearly every aspect of human ...

Revised: This Reviewed Preprint has been revised by the authors in response to the previous round of peer review; the eLife assessment and the public reviews have been updated where necessary by the ...

Aging is an independent risk factor for many chronic diseases, including cancer and cardiovascular, pulmonary, and neurodegenerative diseases. In recent years, the mechanisms of aging-related ...