Efficacy of conventional synthetic disease-modifying antirheumatic drugs, glucocorticoids and tofacitinib: a systematic literature review informing the 2013 update of the EULAR recommendations for ...

Most tissues express glucocorticoid receptors but tissue-specific modulation of this receptor affects homeostasis, immune responses and cell differentiation mediated by glucocorticoids. This ...

Phosphorylated CREB modulates the transcription of several genes that code for molecules that are involved in neuronal plasticity, including tyrosine hydroxylase and BDNF.

Background Glucocorticoid injection (GCI) and surgical rotator cuff repair are two widely used treatments for rotator cuff tendinopathy. Little is known about the way in which medical and surgical ...

Figure 2 Sex hormones, glucocorticoids, and their crosstalk in BAT regulation. Estrogens stimulate whereas androgens inhibit brown adipose tissue (BAT) activity directly and indirectly via the brain.

Site-specific protein bioconjugation methods have enabled the development of new therapeutics and materials, and further development of existing techniques has expanded the compatible library of ...

Article citations More>> Chourpiliadis, C. and Aeddula, N.R. (2023, July 17) Physiology, Glucocorticoids. National Center for Biotechnology Information. https://pubmed.ncbi.nlm.nih.gov/32809732/ has ...

What does this study add? Several evidences now seem to confirm that the treatment of the night up-regulation of the immune/inflammatory reaction at lest in rheumatoid arthritis, is more effective ...

1 Division of Pediatric Nephrology, Department of Pediatrics, Washington University, Saint Louis, MO, United States 2 Departments of Medicine and Cell Biology, Washington University, Saint Louis, MO, ...

Mitotane reduces cortisol synthesis through the inhibition of 11B-hydroxylase, 18-hydroxylase, 3-α hydroxylase, hydroxysteroid dehydrogenase and several cholesterol side chain cleavage enzymes. [18] ...

Estrogens and Glucocorticoids Inhibit Endothelial Vascular Cell Adhesion Molecule-1 Expression by Different Transcriptional Mechanisms ...

Amplification of the human epidermal growth factor receptor 2 (HER2, Erb B2) gene leads to persistent activation of signaling pathways that enhance cell proliferation, resistance to apoptosis signals, ...