Glucocorticoids are essential for the normal development and functioning of the adrenal medulla. ... Hamburg, Germany) and tyrosine hydroxylase (Boehringer Mannheim, Mannheim, Germany), ...

Yes, I do think we need non-glucocorticoid forms of therapy to treat 21-hydroxylase deficiency congenital adrenal hyperplasia.The most common form of congenital adrenal hyperplasia (CAH) is a ...

Four antiglucocorticoid drugs have been studied in depressed patients: metyrapone, aminoglutethimide, and ketoconazole, all cortisol-synthesis inhibitors, and mifepristone (RU 486), a ...

A stable glucocorticoid dose was maintained for 4 weeks, and the dose was then adjusted to a target of 8.0 to 10.0 mg per square meter of body-surface area per day (hydrocortisone dose equivalents ...

Neurocrine Biosciences, Inc. (Nasdaq: NBIX), today presented the CAHtalyst™ Pediatric Phase 3 clinical study baseline characteristics data for children and adolescents with congenital adrenal ...