Insulin glulisine mimics the pharmacokinetic and pharmacodynamic profiles of physiological human insulin, has a rapid onset, peak effect at 1 h, and a shorter duration of action (~4 h).

Purpose: The pharmacology, pharmacokinetics, clinical efficacy, adverse effects, drug interactions, and role in therapy of vildagliptin for the treatment of type 2 diabetes mellitus were reviewed ...

Vildagliptin is among a new class of oral diabetes medications currently being studied. The mechanism of these agents involves inhibition of dipeptidyl peptidase IV (DPP4), the enzyme that contributes ...

IT has been reported that glycine has three polymorphic forms: (1) an ordinary form, α, the crystal structure of which was determined in 1939 by Albrecht and Corey1, a precise analysis having ...

Analogs of proline can be used to expand the chemical space about the residue while maintaining its uniquely restricted conformational space. Here, we demonstrate the incorporation of 4R-methylproline ...