Great Dane puppies have about two minutes of being sweet and little before they grow into big (and still very sweet) house ...

Great Dane puppies are so big, even when they're little. They're born a pretty normal puppy size, but quickly skyrocket into ...

An adorable Great Dane has become a supermom after birthing 21 pups over the course of 27 hours. ... Big dogs, like Danes, tend to have larger litters proportionate to their larger size.

Cleo, a Great Dane in Arizona, was said to be doing well Monday after giving birth to 19 -- yes, 19 -- puppies over the weekend. Doctors at the Kingman Animal Hospital in Kingman, Arizona, helped ...

A North Carolina family’s Great Dane puppy plunged 50 feet into an old well in the woods Saturday but emerged miraculously unscathed after firefighters rescued her. The 11-month-old pup named ...

The Great Dane puppy is looking around at everybody, wondering who the mean person was that kicked it for no reason! Jasmin's video went viral - it's been viewed almost 16 million times, ...

Great Dane dogs are huge bundles of joy, and despite their size, they are one of the soppiest breeds around. One Great Dane that has captured hearts on TikTok is Margot the mottled gray dog. In a ...

MIAMI (CBSMiami) - Two South Florida dog owners are asking for the public's help after four Great Dane puppies were stolen from a Homestead backyard. "It's like your kid, your own children were ...