The taccalonolides are microtubule stabilizers isolated from plants of the genus Tacca. Taccalonolide AF is 231 times more potent than the major metabolite taccalonolide A and differs only by the ...

Merchant shipping is continuing to pass through the Strait of Hormuz despite Israel's attacks on Iran on Friday, the multinational, U.S.-led Combined Maritime Force said, although some shipowners ...

Most importantly, microtubule depolymerization after either colchicine or cold exposure returned cardiocyte contractile function to normal, 9 and we have recently extended this finding to the tissue ...

A series of novel cyclopropylamide analogues of combretastatin-A4 (CA-4) were designed and synthesized. Most of them had significant in vitro antiproliferative activities, particularly for compounds ...