Mechanism: Sibeprenlimab is a monoclonal antibody that targets APRIL (A PRoliferation-Inducing Ligand), a key cytokine in the first hit of the pathogenic cascade. Relation to 4-Hit Cascade: By ...

The approach to IgA nephropathy management is evolving from a one-size-fits-all model to a personalized, risk-stratified framework: ...

Objective: Patients with chronic kidney disease (CKD) are at higher risk for cardiovascular disease (CVD) than patients in the general population. One potentially modifiable risk factor for CVD in ...

Kidney Disease: Improving Global Outcomes (KDIGO) CKD-MBD Work Group. KDIGO clinical practice guideline for the diagnosis, evaluation, prevention, and treatment of Chronic Kidney Disease-Mineral and ...

The Kidney Disease: Improving Global Outcomes (KDIGO) group has released its 2025 Clinical Practice Guideline for the Evaluation, Management, and Treatment of Autosomal Dominant Polycystic Kidney ...

Researchers at Rice University have developed a new machine learning (ML) algorithm that excels at interpreting the "light signatures" (optical spectra) of molecules, materials and disease ...

In the treatment of MCD, the KDIGO guidelines recommend RTX as a second-line therapy ... The estimated glomerular filtration rate (eGFR) was calculated using the CKD-EPI formula. Baseline was defined ...

This study adheres to the Strengthening the Reporting of Observational Studies in Epidemiology reporting guidelines for cohort ... category A3 (>300 mg/g); CKD, chronic kidney disease; GFR, glomerular ...

The researchers plan to further study the algorithm at health systems across the country. Infusion care in crisis: Why 82% of centers struggle to access the data they need Recommended Whitepaper ...

Background: Diabetic kidney disease (DKD) is a common and serious complication ... and ChatGLM4 generated 2 versions of PEMs based on American Diabetes Association(ADA) guidelines and without ADA ...