Researchers in Korea have found new substances that are effective in restoring memory and suppressing dementia. A joint ...

German biopharmaceutical company HepaRegeniX has begun dosing subjects in a Phase Ib trial of HRX-215 in subjects undergoing ...

ALPK3 belongs to the αprotein kinase family, a subfamily of the atypical protein kinase family distinguished by its unique α kinase domain. 9 Based on the transcriptional data on human tissues, the ...

PINK1, a ubiquitin kinase that causes early onset Parkinson’s disease when mutated, functions as an early warning system for faltering mitochondria (Valente et al., 2004). Under normal conditions, ...

The anterior is to the left, the posterior is to the right, and the ventral is at the bottom. Arrows point to the vulvae. Scale bar = 50 µm (D) Model of SUR-6 PP2A-B55 regulation by KIN-4, ENSA-1, and ...

Researchers from the Icahn School of Medicine at Mount Sinai have introduced KiNet, an interactive web portal designed to explore kinase-substrate interactions in human cellular systems. These ...

Researchers from the Icahn School of Medicine at Mount Sinai have introduced KiNet, an interactive web portal designed to explore kinase-substrate interactions in human cellular systems. By ...

In summary, this study not only demonstrates PKM2 function as a histidine kinase to phosphorylate PGAM1 to coordinate the glycolysis with its shunts during the rapid proliferation of the tumor cells, ...

Manipulating protein kinase function, by controlling the active site, is a promising therapeutic and investigative strategy to mitigate and study diseases. Kinase active sites share structural ...

In some cancers, mutations in the kinase lock it together, keeping it abnormally active. Credit: Eric Smith/Chris Garcia/Howard Hughes Medical Institute. Stanford researchers have captured the 3D ...