Why are players wearing No. 4 across MLB June 2? June 2 is Lou Gehrig Day in MLB, designed to honor the late Yankees legend and raise awareness and funding for ALS. What is ALS?

Cedars-Sinai has created a lifelike model of the mysterious and fatal disease that could help identify a cause of the illness as well as effective treatments.

Monday was Lou Gehrig Day, when the Major Leagues paid tribute to the Yankees’ first baseman, who died on June 2, 1941, from Amyotrophic Lateral Sclerosis.

Gehrig delivered a farewell speech now known as the "Luckiest Man Alive" speech to Yankee Stadium fans in 1939, two weeks after he was diagnosed with ALS, in an event labeled Lou Gehrig Day.

Seattle Mariners will honor Lou Gehrig and raise ALS awareness on June 3 with No. 4 patches and ceremonies. Former NFL star Steve Gleason will throw the first pitch.

Topps Now commemorated Lou Gehrig Day 2025 with a new release of a limited edition, charitable 30-card set featuring some of the biggest stars of the game and The Hobby on a dual-image card with ...

The Mets and Dodgers paid tribute to Lou Gehrig and the fight to find a cure for ALS during Monday night's series opener at Dodger Stadium.

Monday is Lou Gehrig Day at Great American Ball Park as the Cincinnati Reds host the Milwaukee Brewers.

Here is everything to know about how MLB honors Gehrig's legacy while raising ALS awareness.

LOS ANGELES – Ahead of MLB’s official Lou Gehrig Day, the Yankees and Dodgers wore his No. 4 on their jerseys during Sunday’s game at Dodger Stadium. The Yankees are off Monday, celebrated ...

Honor Lou Gehrig Day by exploring 5 of his most iconic baseball cards, including his 1933 Goudey and rare rookie card - must-haves for vintage baseball card and sports card collectors.