San Francisco 49ers running back Christian McCaffrey could make his season debut during Week 7 against the Kansas City Chiefs ...

After swapping his cleats for a microphone, the spotlight during Sunday's game between the San Francisco 49ers and Arizona ...

Half of the 10 Sunday afternoon games on the Week 5 NFL schedule are divisional matchups, but oddly, none of them features a ...

SportsLine's model simulated Arizona Cardinals vs. San Francisco 49ers 10,000 times and made its Week 5 NFL picks, ...

The NFL denied the San Francisco 49ers' request to change to an all-white uniform set before the hottest game in Levi's ...

Nine teams scored 30-plus points and three games combined for 60 or more. Captain Kirk Cousins threw for a whopping 509 ...

San Francisco's defense rebounded against the Patriots but faces a tougher test in Murray's dynamic playmaking ability. Brock ...

An Aussie had a career day, and the rookie throwers are starting to make their mark as the NFL reached week five.

Why San Francisco 49ers changed their uniform for NFL Week 5 game against Arizona Cardinals Sunday, and why it's not the ...

In the past three weeks, Israel turned its attention north to Lebanon. Airstrikes and a ground invasion have killed around ...

Using Samuel in the backfield isn’t a novel concept, but it’s one the 49ers have gone away from since his breakout All-Pro ...