When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication ...

After a finite number of divisions, cells simply give up. As each round of replication trims their telomeres-the protective ...

We have long struggled to determine how the first living organisms on Earth came together. Now, surprising evidence hints ...

Mitochondrial DNA (mtDNA) exhibits a degree of resistance to mutagenesis under genotoxic stress, and this study on the mitochondrial Transcription Factor A (TFAM) presents valuable data concerning the ...

In eukaryotic cells, present in animals, plants, fungi and protists, most DNA is concentrated in the nucleus. This membrane-bound organelle serves as the command center of the cell, protecting the ...

DNA replication is a semi-conservative process in which half of the newly synthesized strands (daughters) are derived from the original strands (mothers). The confirmation of semi-conservative ...

DNA, often called the blueprint of life, is built from four chemical building blocks known as deoxy-nucleoside triphosphates (dNTPs)—dATP, dTTP, dGTP, and dCTP. Cells constantly need these molecules ...

This transcript has been edited for clarity. For more episodes, download the Medscape app or subscribe to the podcast on Apple Podcasts, Spotify, or your preferred podcast provider. Dr Liu is a ...