Why do problems occur with a special variant of 'protein glues', the split inteins, that severely limit their use in producing proteins? A team has now answered this question.

Proteins serve as the fundamental components of life, composed of folded peptide chains made up of a sequence of amino acids.

Proteins are the building blocks of life. They consist of folded peptide chains, which in turn are made up of a series of ...

Key structural and mechanistic insights into BSEP transporter mutations that lead to improper protein folding and functionFindings have ...

Kanazawa University and colleagues have achieved a breakthrough in understanding sperm DNA packaging. Using high-speed atomic force microscopy (HS-AFM), they captured the real-time process of ...

Protein folding is the process by which proteins achieve their mature functional (native) tertiary structure, and often begins co-translationally. Protein folding requires chaperones and often ...

By investigating how lipid-soluble Cer is transported between cells, the researchers demonstrated that high-density lipoprotein (HDL) serves as the primary carrier for Cer transport. Upon reaching ...

The endoplasmic reticulum (ER) is the portion of the cell responsible for manufacturing and folding proteins. Proteins are ...

They’re easy to whip up when all you need a quick protein hit after a hard workout or on-the-go. But, we probably don’t need to tell you that it’s possible to have too much of a good thing.

Singapore researchers are using Google DeepMind’s AlphaFold to understand the intricate protein interactions at play in ...