Drug resistance to doxorubicin is mediated through the ABCG2 protein by the TMEM158 gene.ABCG2 protein ( ATP-binding cassette sub-family G member. Is an efflux pump protein that actively transports ...

By analyzing proteomes and transcriptomes across tissues like the brain, heart, and skin, they uncovered proteins linked to ...

regulate gene expression, maintain pH balance, and serving as an energy source during specific metabolic conditions. They are called the building blocks of life. Given their multifaceted roles, a ...

StitchR makes it possible to deliver larger payloads with current vectors, expanding the list of diseases targetable by gene therapies.

StitchR, a new gene therapy technique, delivers large genes in two parts to treat muscular dystrophies by restoring critical proteins in animal models.

Gene therapy can effectively treat various diseases, but for some debilitating conditions like muscular dystrophies there is a big problem: size.

Orphan genes, found only in specific lineages, are key drivers of new functions and phenotypic traits. This discovery lays a ...

Gene therapy for some diseases, including Duchenne muscular dystrophy (DMD), can be tricky because the needed gene is often ...

Gene therapy can effectively treat various diseases, but for some debilitating conditions like muscular dystrophies there is ...

These mutations impair ribosome production, disrupting protein synthesis critical for blood ... regulatory elements to ensure ...

Rice leaf veins are essential for plants' growth and development. They help support the leaves and transport important ...