Much of the difficulty of determining the contributions of individual residues to protein structure and function stems from the need to generate and evaluate a large number of mutants. The ...

A research team has identified a molecular mechanism that coordinates the operation of the N-methyl-D-aspartate (NMDA) ...

A study from VIB-KU Leuven reveals how the interaction between the proteins GPR158 and PLCXD2 regulates synaptic maturation.

There are only a few experts worldwide and social awareness is lacking. Unraveling the structure and function of proteins to understand diseases and develop therapies An international team of ...

A study has found that an ancient protein motif that binds to nucleic acids is functionally "ambidextrous." This means that ...

The new model, called BaseFold, enables more reliable 3D structure predictions for larger and more complex proteins and, according to the company, is “poised to greatly accelerate AI-based drug ...

Although the rational protein design approach offers an increased possibility of beneficial alterations, it is not easy to accurately predict the sequence-structure-function relationship, particularly ...

Researchers observe how fluctuations in ovarian hormones shape the structure and function in the mouse hippocampus, with ...

After you eat a meal, zinc is taken up by the cells of your body. Inside each cell, zinc binds to proteins to support their structure and function. Researchers estimate that up to 10% of all proteins ...