One of the largest international genetic studies of congenital heart disease (CHD) highlights the significance, in particular forms of the disease, of spontaneous gene mutations not inherited from ...

Congenital heart disease (CHD) refers to a range of heart defects that are present at birth. It is a significant cause of morbidity and mortality among infants and children worldwide. Recent ...

Over the years, scientists have attempted to map the genetic ... this gene to heart defects in humans, would be important avenues to explore in the future. “Down syndrome affects a lot of people, and ...

We used an anatomic and clinical classification of CHD based on the International Paediatric and Congenital Cardiac ... anomalies and/or non-cardiac defects and adjustement for maternal age ...

Ostium secundum atrial septal defect (OSASD) occurs as an isolated defect in 10% of individuals with congenital heart disease (CHD ... emphasizes the role of genetic factors in the determination ...