Prenatal detection rates of congenital heart disease (CHD) have increased over time, according to a study published online ...

Then, starting with a landmark publication in Cell in 1990, Harvard Medical School researchers uncovered critical insights into the genetic and molecular underpinnings of the disease. Their federally ...

GeneDx CEO Katherine Stueland explains how her company screens babies’ DNA for mutations that cause thousands of treatable ...

Researchers have found that risk for developing dementia is related to genetic risk for coronary artery disease.

An international multidisciplinary team has demonstrated for the first time that CRISPR-based gene activation (CRISPRa) can ...

The commercial success of existing lipid-lowering medications highlights the enormous market potential for effective ...

Vascular sites have distinct susceptibility to disease. Here, through single cell epigenomic profiling and predictive machine ...

This study provides valuable insights into human valve development by integrating snRNA-seq and spatial transcriptomics to characterize cell populations and regulatory programs in the embryonic and ...

A surprising number of adults in ICUs at Penn had undiagnosed genetic conditions, pointing to a need for universal testing in ...

Scientists have discovered more than 100 new epigenetic biomarkers that may help predict cardiovascular disease risk and inform preventive care measures to improve long-term outcomes, according to a ...

Multisystemic smooth muscle dysfunction syndrome (MSMDS) is a rare condition associated with stroke, aortic dissection (tearing) and death in childhood. Currently, there is no effective treatment or ...

Genetics research in Parkinson's disease has identified over 100 risk loci, yet translating these findings into understanding ...