Uncovering a new genetic code in archaea opens doors for bioengineering applications

The genetic code is the recipe for life, and provides the instructions for how to make proteins, generally using just 20 ...

DNA transcription is a tightly choreographed event: How RNA polymerase II regulates the dance

Life's instructions are written in DNA, but it is the enzyme RNA polymerase II (Pol II) that reads the script, transcribing ...
eLife

Decapping activators Edc3 and Scd6 act redundantly with Dhh1 in post-transcriptional repression of starvation-induced pathways

Multi-omics analyses reveal redundant functions of yeast mRNA decapping activators Scd6 and Edc3 in facilitating recruitment of helicase Dhh1 and accelerating degradation of transcripts required for ...
C&EN

These archaea built a distinct genetic code to put pyrrolysine in proteins

Pyrrolysine is an important component of methyltransferase enzymes, which the archaea use to metabolize methylamine in the environment. “The need for that metabolism and availability of the machinery ...