The Met receptor tyrosine kinase is the prototypic member of a small subfamily of growth factor receptors that when activated induce mitogenic, motogenic, and morphogenic cellular responses. The ...

Receptor tyrosine kinases (RTKs) regulate many critical biological processes such as cell growth, differentiation, and survival through the recruitment of intracellular signaling molecules. The ...

The intricate regulation of receptor tyrosine kinases (RTKs) underpins a vast array of cellular responses that are essential for growth, differentiation and survival. In particular, the interplay ...

Written and edited by experts in the field, "Signaling by Receptor Tyrosine Kinases" from Cold Spring Harbor Laboratory Press discusses the mechanisms underlying receptor tyrosine kinase signaling ...

View all available purchase options and get full access to this article. Corresponding author: Ben Ho Park, MD, PhD, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of ...

Syk Kinase We are also actively investigating the regulation of Syk tyrosine kinase binding to membrane immune receptors and other signaling proteins. Syk recognizes doubly phosphorylated regions of ...

Scientists are gaining a new understanding of a key signaling pathway in embryo development, tissue maintenance, and cancer genesis. [Chepko/Getty Images] Researchers at the University of Illinois ...

Mutations in the Fms-like tyrosine kinase 3 (FLT3) receptor in acute myeloid leukemia ... Schlessinger, J. Cell signaling by receptor tyrosine kinases. Cell 2000;13:211-225. Crossref.

First complete interactome map of human receptor tyrosine kinases and phosphatases. ScienceDaily . Retrieved January 29, 2025 from www.sciencedaily.com / releases / 2017 / 01 / 170105123112.htm ...

Zsebo, KM, Williams, DA, Geissler, EN, et al. Stem cell factor is encoded at the S1 locus of the mouse and is the ligand for the c-kit tyrosine kinase receptor. Cell 1990;63:213-224 Crossref ...

In 2011, Igor Stagljar, a professor in the University of Toronto's Donnelly Centre, came across a study that genetically linked two genes in the cell to a hard-to-treat (triple negative) breast ...