Renal hypoperfusion occurs as a result of reduced cardiac output, resulting in the activation of the renin–angiotensin–aldosterone system, which compensates for the hypoperfusion. However ...

Blockade of the renin–angiotensin system has beneficial effects in patients with diabetic nephropathy; however, this treatment can induce aldosterone breakthrough and thus become ineffective.

physicians must be aware of clinical circumstances that may promote the development of hyperkalemia The renin–angiotensin–aldosterone system (RAAS) has a pathogenetic role in several edematous ...