with adverse events consistent with the known effects of targeting the renin-angiotensin-aldosterone system -- an increased risk of hyperkalemia and hyponatremia and decreases in the eGFR ...

Angiotensin-converting enzyme (ACE) inhibitors are oral medications that lower blood pressure. They are used to treat a variety of heart-related conditions including high blood pressure, coronary ...

a Estimated cost, based on average wholesale price (Drug Topics Red Book, 1999), to the pharmacist for a one-month supply at the usual starting dosage.

Nature Research Intelligence Topics enable transformational understanding and discovery in research by categorising any document into meaningful, accessible topics. Read this blog to understand ...

Figure 3. Simplified diagram of the renin-angiotensin-aldosterone system. Angiotensinogen is cleaved by renin to angiotensin I (Ang I). Ang I is then converted by angiotensin-converting enzyme (ACE) ...

Hypertension was also prevented by the tumor necrosis factor-α antagonist etanercept. Whole animal studies of the proinflammatory effects of aldosterone may be confounded by systemic effects on sodium ...