The Cardinals beat the 49ers, 24-23, on Sunday afternoon in Santa Clara, a win that changed the outlook of their season.

According to the latest odds available at DraftKings Sportsbook, the Seahawks are three-point underdogs at home for this week ...

The 49ers just blew another 10-point fourth quarter lead and lost 24-23 to the Arizona Cardinals. Now the 49ers are 2-3. Here ...

This is the live blog for the San Francisco 49ers' Week 5 home game against the Arizona Cardinals. I will update this ...

San Francisco veteran kicker Jake Moody suffered a high right ankle sprain while attempting to make a tackle on a kick return ...

The 49ers are a 7.5-point favorite over the Cardinals in NFL Week 5 odds for the game, courtesy of BetMGM Sportsbook. San ...

One of the top runners in the league will be featured when Jordan Mason and the San Francisco 49ers host the Arizona ...

The 49ers (2-3) blew a 10-point, fourth-quarter lead and fell 24-23 to the visiting Arizona Cardinals in record heat at ...

The missing element? It’s sticking out like a sore Achilles. McCaffrey’s absence underscores just how essential he was to the ...

We’re now five weeks into the NFL season, and there are far more questions than answers for the San Francisco 49ers.

The San Francisco 49ers just beat the New England Patriots 30-13. Here are the 49ers' grades for this performance. BROCK ...

NFL Week 5 odds, picks, predictions, TV and streaming information for the Sunday football game between the Arizona Cardinals ...