The Cardinals beat the 49ers, 24-23, on Sunday afternoon in Santa Clara, a win that changed the outlook of their season.

Tom Brady reminisced on facing San Francisco 49ers quarterback Brock Purdy in 2022, the final season of his career.

According to the latest odds available at DraftKings Sportsbook, the Seahawks are three-point underdogs at home for this week ...

The 49ers just blew another 10-point fourth quarter lead and lost 24-23 to the Arizona Cardinals. Now the 49ers are 2-3. Here ...

San Francisco veteran kicker Jake Moody suffered a high right ankle sprain while attempting to make a tackle on a kick return ...

The Arizona Cardinals fumbled their way into the second half but rallied back for a 24-23 win over the San Francisco 49ers on ...

Two weeks after faltering on the road to the Los Angeles Rams, the 49ers blew another 10-point lead and exited with a 24-23 ...

The 49ers' biggest issue was something that's plagued them all season: They had six trips to the red zone and scored just one ...

Two weeks after faltering on the road to the Los Angeles Rams, the 49ers blew another 10-point lead and exited with a 24-23 ...

Arizona shuts down San Francisco in second half to stage late rally after trailing by as much as 13 points on the road.

The San Francisco 49ers just beat the New England Patriots 30-13. Here are the 49ers' grades for this performance. BROCK ...

NFL Week 5 odds, picks, predictions, TV and streaming information for the Sunday football game between the Arizona Cardinals ...