The ZZ genotype of alpha-1 antitrypsin deficiency (AATD) is associated with COPD regardless of smoking. Heterozygous MZ-AATD is recognised as a moderate deficiency state, increasing the risk of COPD ...

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The global alpha-1 antitrypsin deficiency (AATD) market is expanding, driven by advances in diagnosis, treatment, and growing awareness. Key players like Grifols, CSL Behring, and Pfizer lead ...

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Alpha-1 antitrypsin deficiency (AATD) is an inherited genetic disorder that affects the lungs and/or liver, leading to early onset emphysema and liver disease, and for which there is significant ...

Article Summary Iron Studios unveils a new DC Comics 1/10 Art Scale statue featuring The Flash in classic style Statue captures Barry Allen mid-sprint, showcasing dynamic motion and vibrant red ...

To the point Hereditary disease alpha-1-antitrypsin deficiency: Researchers have discovered why some patients remain healthy despite a genetic defect, while others develop severe liver fibrosis Deep ...

KNOXVILLE, Tenn. (WATE) — The Cradle of Country Music Park’s $1.2 million transformation is open to the public nearly six years after funding for the project was first approved. The fencing on ...

Mutants of members of the serpin superfamily can undergo nonamyloid aggregation to form polymeric chains that are associated with disease. This is typified by Z alpha-1-antitrypsin (Glu342Lys) that ...

Background: Cetuximab has been shown to improve survival in patients with KRAS wildtype metastatic colorectal cancer. However, high rates of hypersensitivity reactions (HSRs) limit its use, with HSR ...

GSK-5462688 is under clinical development by GSK and currently in Phase II for Alpha-1 Antitrypsin Deficiency (A1AD). According to GlobalData, Phase II drugs for Alpha-1 Antitrypsin Deficiency (A1AD) ...