San Francisco veteran kicker Jake Moody suffered a high right ankle sprain while attempting to make a tackle on a kick return Sunday during the 49ers' 24-23 loss to the Arizona Cardinals at Levi's Stadium,

The Seattle Seahawks and San Francisco 49ers both suffered brutal home upset losses to opponents who each had only one win going into Sunday. Seattle fell 29-20 to the New York Giants, while the 49ers were upset 24-23 by the Arizona Cardinals.

The San Francisco 49ers are up against it on the injury front following their Week 5 loss to the Arizona Cardinals. Unfortunately, updates on in-game injuries were limited Monday morning. Head coach Kyle Shanahan typically speaks with reporters in a conference call Monday afternoon,

The top tight ends for both the Arizona Cardinals and San Francisco 49ers enter the Week 5 divisional showdown between the two teams questionable to play. Both are expected to play, according to ESPN’s Adam Schefter.