The San Francisco 49ers were thought to be among the favorites to represent the NFC in the Super Bowl for a second straight year, but they haven't ...

After swapping his cleats for a microphone, the spotlight during Sunday's game between the San Francisco 49ers and Arizona ...

The 49ers' biggest issue was something that's plagued them all season: They had six trips to the red zone and scored just one ...

Two weeks after faltering on the road to the Los Angeles Rams, the 49ers blew another 10-point lead and exited with a 24-23 ...

Kyler Murray had a long touchdown run in the first quarter and rallied Arizona with two fourth-quarter scoring drives in the Cardinals' 24-23 victory over the San Francisco 49ers on Sunday.

The record-breaking heat at Levi's Stadium on Sunday sent San Francisco 49ers fans to the concourses to watch the game on ...

It’s even hotter than was expected on a record-breaking day at Levi’s Stadium for Sunday’s San Francisco 49ers game — and the ...

SportsLine's model simulated Arizona Cardinals vs. San Francisco 49ers 10,000 times and made its Week 5 NFL picks, ...

Jayden Reed has three straight 100-yard regular-season games dating back to the end of last year with Jordan Love starting at ...

Steelers is one of the rare non-conference NFL rivalries thanks to their postseason history. In fact, their three Super Bowl ...

With record heat descending on the Bay Area on Sunday, the NFL has denied the San Francisco 49ers' request to wear white ...

Using Samuel in the backfield isn’t a novel concept, but it’s one the 49ers have gone away from since his breakout All-Pro ...