The San Francisco 49ers have been practicing in temperatures exceeding 90 degrees this week. Sunday's game against the ...

Why San Francisco 49ers changed their uniform for NFL Week 5 game against Arizona Cardinals Sunday, and why it's not the ...

Who will move on to 2-0 when the San Francisco 49ers (1-0) and Minnesota Vikings (1-0) square off? Christian McCaffrey didn't play, but the 49ers didn't skip a beat when they crushed the New York ...

ARIZONA -- Arizona Cardinals HC Jonathan Gannon doesn't put too much stock into divisional games, though he knows the San Francisco 49ers a bit better thanks to their time together NFC West.

SANTA CLARA -- This is the live blog for the San Francisco 49ers' Week 4 home game against the New England Patriots. I will update this frequently with information and analysis from the press box.

As the San Francisco 49ers gear up for another run at a Super Bowl title, they find themselves with some unexpected holes to fill. All season, the 49ers' roster has been decimated by injuries ...

Here is the NFL's list of everything you need to know when the San Francisco 49ers play the New England Patriots in Week 4 of the 2024 NFL season. Listen to Hall of Fame inductee and former San ...

The San Francisco 49ers will try to stop the bleeding of their two-game losing streak when they host the New England Patriots at Levi’s Stadium on Sunday. The reigning NFC champions are banged ...

The Arizona Cardinals and San Francisco 49ers play on Sunday, Oct. 6, at Levi's Stadium in a game on the NFL Week 5 schedule. Which team will win the NFL Week 5 game? The 49ers are a 7.5-point ...

The San Francisco 49ers are reinforcing the roster with two new additions, while also opening up the practice window for DL Kalia Davis. The injury bug has struck the 49ers over the past four ...