Individuals with a mutation in the gene encoding a zinc transporter, SLC30A8 have an elevated risk of developing type 2 diabetes. Insulin granules that are released from pancreatic β cells ...

Individuals with a mutation in the gene encoding a zinc transporter, SLC30A8 have an elevated risk of developing type 2 diabetes. Insulin granules that are released from pancreatic β cells ...

Genome-wide association studies have previously identified variants in SLC30A8, encoding the zinc transporter ZnT8, associated with diabetes risk. A rare variant association study has now ...

SLC30A8 codes for a zinc transporter protein called ZnT8 that brings zinc into insulin-releasing beta cells in the pancreas. One particular variation in this gene has been known to increase the ...

Researchers have identified the biological mechanism through which a genetic variant protects against type 2 diabetes. The study finds that changes in a gene which makes zinc transporter proteins ...

"Given that type 2 diabetes is a growing global epidemic, it has long seemed that a drug targeting the protein SLC30A8 makes, namely ZnT8 or zinc transporter 8, would potentially have a huge ...

Medindia » News » Drug News » New Drug That Targets ‘Hyperactive’ Zinc Transporter May Lower Diabetes Risk by Madhumathi Palaniappan on Dec 17 2016 5:38 PM Faulty genes may cause disease.

“A rare loss-of-function allele p.Arg138* in SLC30A8 encoding the zinc transporter 8 (ZnT8), which is enriched in Western Finland, protects against type 2 diabetes (T2D).

Scientists at the U.S. Department of Energy’s (DOE) Brookhaven National Laboratory have determined the atomic-level structure of a zinc-transporter protein, a molecular machine that regulates levels ...

People with a mutation in SLC30A8 - the gene encoding a zinc transporter have a higher risk of developing type 2 diabetes, says study. Insulin granules that are released from pancreatic β cells ...