The San Francisco 49ers joined local cancer warriors to create artwork that symbolized strength and they later wore on custom Levi's® jackets to the team's Week 4 Crucial Catch matchup presented ...

Two weeks after faltering on the road to the Los Angeles Rams, the 49ers blew another 10-point lead and exited with a 24-23 ...

The San Francisco 49ers have been practicing in temperatures exceeding 90 degrees this week. Sunday's game against the ...

The game against the Arizona Cardinals marked the second time this season that San Francisco (2-3) blew a double-digit lead ...

ARIZONA -- Arizona Cardinals HC Jonathan Gannon doesn't put too much stock into divisional games, though he knows the San Francisco 49ers a bit better thanks to their time together NFC West.

ARIZONA -- The Arizona Cardinals and San Francisco 49ers have released their final injury report of the Week 5 practice slate. Both teams have some massive names marked as questionable.

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Parents of Addicted Loved Ones is hosting its 2nd annual Power of Hope Conference to bring together those with a connection to substance abuse disorder. Wijaya House, a coffee/book/flower shop ...

McBride has 14 catches for 122 yards so far this season. On Sunday in San Francisco (Santa Clara), record heat for early October is expected. With a projected high of 95, the 49ers wanted to switch ...