'End-stage' hypertrophic cardiomyopathy (HCM) is one of the most serious manifestations of HCM, yet its etiology remains poorly understood. Here, Yacoub et al. discuss recent advances in our ...

Motion estimation constitutes a significant computational part of video compression standards such as MPEG4. The present work focuses on the development of a reconfigurable systolic-based architecture ...

Fifty years ago, the first modern reports of what we now recognise as hypertrophic cardiomyopathy (HCM) were written by a surgeon, Sir Russell Brock,1 and a pathologist, Donald Teare.2 These classic ...

Among patients without CHF but with echocardiographic evidence of amyloid infiltration of the LV, tissue Doppler detected only diastolic abnormalities and systolic function appeared preserved. 13 ...

Background The presence of mitral valve prolapse (MVP) in congenital heart disease (CHD) patients is not well described. Tetralogy of Fallot (TOF) is the most common cyanotic CHD associated with ...

Previous studies have shown that 25–30% of patients with HCM have a resting pressure gradient across the left ventricular outflow tract caused by systolic anterior motion of the mitral valve ...

Low systolic tissue velocity at maximal stress (<5.5 cm/s) predicts induced wall-motion abnormality. 36 The MYocardial Doppler In Stress Echocardiography (MYDISE) study found that tissue velocities ...