Department of Pharmaceutical and Medicinal Chemistry, Institute of Pharmaceutical Sciences, University of Tuebingen, Auf der Morgenstelle 8, Tuebingen 72076, Germany IFIT Cluster of Excellence EXC ...

The key molecules and pathways involved—namely ... Abbreviations: TFR1, Transferrin Receptor 1; TF, Transferrin; STEAP3, Six-transmembrane epithelial antigen of the prostate 3; ROS, eactive Oxygen ...

Convergence of additional signal pathways with vitamin D modulate antimicrobial ... other ligands The vitamin D receptor (VDR) functions as a receptor for both vitamin D and secondary bile acids.

Hotter temperatures may render natural insect repellents less effective against mosquitoes, according to a new study. Hotter temperatures may render natural insect repellents less effective ...

Pathways of VD effects on DN ... Vitamin D-binding protein; VDR, Vitamin D receptor; VDRAs, Vitamin D receptor activators.

Cardiovascular disease (CVD) is the leading cause of death and disease burden worldwide. Macrophages are important components ...

We aimed to define the impact of VD on oesophageal allergic inflammation. Design We assessed the genomic distribution and function of VD receptor (VDR) and STAT6 using histology, molecular imaging, ...

Crosstalk with the Jun N-terminal kinase (JNK), p53 and nuclear-receptor pathways provide specific examples of the diversity of mechanisms that exist to link NF-κB function to other important ...

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The dendritic cell receptor Clec9A facilitates processing of dead cell-derived antigens for cross-presentation and the induction of effective CD8 + T cell immune responses. Here, we show that this ...