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Using the Canadian Light Source at the University of Saskatchewan, the researchers identified for the first time the crystal structures of a human protein (TMPRSS11D) that viruses use as a doorway ...
The most common method used to study protein structures is X-ray crystallography. With this method, solid crystals of purified protein are placed in an X-ray beam, and the pattern of deflected X ...
and the results point the way to using even smaller crystals -- or even uncrystallized proteins and other biomolecules -- for structure analysis. Using SLAC's Linac Coherent Light Source (LCLS), a ...
Because a crystal structure is really an average of the arrangements of the atoms in millions of protein molecules in the crystal, the tentacles, which are in constant motion, would be an ill ...
The crystal structure of the protein, called Reb1, provides insight into aging and cancer, according to Deepak Bastia, Ph.D., Endowed Chair for Biomedical Research in the MUSC Department of ...
A research team at Weill Cornell Medical College has solved the 3D crystal structure of a member protein in one of the most important classes of human proteins — the G protein-coupled receptors (GPCRs ...
Scientists at Tokyo Tech have developed a new cell-free protein crystallization (CFPC) method that is expected to advance research in structural biology. The technique will enable the analysis of ...
“EM is a widely applied technique to study the structure of proteins and membranes, but it is still less common than X-ray diffraction of prepared crystals. However, crystallization of membrane ...
Tests of these mutants found one where the complex was stable enough to obtain a crystal of the proteins, confirming that the AlphaFold-predicted structure was accurate. In addition, they used ...
Separately, the University of Washington's David Baker was honored for developing software that could design entirely new proteins with specific structures. The award makes for a bit of a theme ...
Knowing the crystal structure of this "doorway" protein, says Fraser, is key to finding helpful drugs to stop coronavirus and influenza viruses, because it is very similar to other important ...