In concord, the expressions of IRGs related to antigen processing and presentation (B2m, Cd74, Tap1 and Tapbp), lymphocyte recruitment (Cxcl9 and Cxcl10) and signalling transduction (Stat1 and Irf1) ...

Through the destabilization of CIITA, the human cytomegalovirus-encoded protein pUS28 antagonizes the expression of the HLA-II molecules CD74/Ii, HLA-DR, HLA-DQ, HLA-DM, and HLA-DP, diminishing the ...

Juvenile idiopathic arthritis (JIA), a type of arthritis commonly occurring in children, is a chronic, inflammatory condition that affects the joints, causing pain, swelling, stiffness, and limiting ...

Juvenile idiopathic arthritis (JIA), a type of arthritis commonly occurring in children, is a chronic, inflammatory condition ...

Soluble CD74 may degrade when sera are kept frozen for at least a year. Consequently, subsequent studies tested an ELISA where whole CD74 was incorporated as an antigen to increase the number of ...

Background: CD74 is involved in the assembly of and the prevention of premature peptide-binding to major histocompatibility complex (MHC) class II. IgG autoantibodies directed against CD74 have been ...