The elasticity and stability of red blood cells are regulated by protein 4.1R interactions with the spectrin-actin network and with membrane associated proteins. The ability to reversibly change ...

Abstract:        Obesity, a growing global issue, has been closely associated with an increased risk of various cancers, especially breast cancer. El ...

Fava bean protein ... structure, increased surface charge, and hydrophobicity that favored emulsifying activity. On the other hand, undue hydrolysis should be avoided because it might negatively ...

Two key protein structures in the body are being visualized for the first time, thanks in part to the latest technology in ...

Healthy cells are constantly breaking down proteins and building up new ones with the help of enzymes aptly named unfoldases, ...

When the antibiotic bedaquiline was introduced in 2012, it was the first new tuberculosis drug in over 40 years. Bedaquiline ...

A team at the Centro Nacional de Investigaciones Cardiovasculares (CNIC), led by Jorge Alegre-Cebollada, has developed an ...

The unfolded protein response (UPR) is a crucial signaling network that preserves endoplasmic reticulum (ER) homeostasis, impacting both health and disease. When ER stress occurs, often due to an ...

Despite decades of research, its full behaviour remained a mystery, mainly because the protein is heavily glycosylated ... adding significant complexity to its structure . Using molecular ...

When Alphabet announced in 2021 that its AlphaFold AI could predict the structure of almost every known protein, it was a major story, not just in the pharma world, but beyond. Yet, that was far ...

This important study presents a compelling theoretical framework for understanding phase separation of membrane-bound proteins, with a focus on the organization of tight junction components. By ...