Centromeres, specialized regions located at the center of chromosomes, are critical for ensuring proper cell division. During ...

Recent breakthroughs in understanding the prostaglandin D2 (PGD2) receptor 1 (DP1) are paving the way for innovative ...

“RibbonFold outperforms other AI-based prediction tools like AlphaFold, which were trained only to predict correctly folded globular protein structures.” Eclipsing the gold standard RibbonFold builds ...

The researchers devised an innovative metric, known as the effective strain, [2] to detect small but important changes in protein structure that are linked to stability. Looking at thousands of ...

told Nature that he's been using the tool for predicting the structure of proteins that interact with DNA when copying genomes and experiments show the predictions are mostly accurate. However ...

Failure to fold properly or maintain its three-dimensional structure can disrupt protein function and lead to disease. Insight into how protein folding stability is maintained will shed further ...

Department of Biomedical and Clinical Sciences, Cell Biology, Faculty of Medicine, Linköping University, Linköping 581 85, Sweden Ikerbasque, Basque Foundation for Sciences, Department of Physiology, ...

Themed on protein designs across globular and disordered proteins as well as their ... acid substitutions that would have the desired effects on the multistate proteins stability and the rates of ...

In a recent study posted to the bioRxiv* preprint server, researchers evaluated the stability and expression of mutations in the spike (S) protein of severe acute respiratory syndrome coronavirus ...