Immunoreagents, most commonly antibodies, are integral components of lateral flow ... introduced to also facilitate recombinant purification. Through molecular dynamics simulations, we elucidate the ...

Dr. Elias Theodorou, Ph.D., is a molecular biologist with over 25 years of experience in cancer research, stem cell differentiation, and gene delivery. He is the co-founder of Protos Biologics Inc., ...

Top view of the scFv antibody fragments specific for fluorescein isothiocyanate (FITC; clone FITC8), MUC1 peptide (Muc159), and cholera toxin (&β-subunit) (clone CT17) showing the molecular ...

Methods: Herein, we present a phage display-derived biosensing platform through genetic engineering of the TS77 antibody variable domains ... The single chain variable fragment (scFv) gene of TS77 was ...

United States Bispecific antibodies (bAbs) that engage cerebrovascular targets, induce transport across the blood-brain barrier (BBB), and redistribute to secondary targets within the brain parenchyma ...

After washes, 50 μL of unpurified scFv-containing bacterial culture supernatants ... When classically performed, antibody discovery requires numerous rounds of molecular (structure, PTMs…), ...

DUBLIN--(BUSINESS WIRE)--The "PD-1 x VEGF and PD-L1 x VEGF Bispecific Antibodies ... clinical profile and molecular structure of drug candidates and business deals from an industry perspective ...

Molecular Cancer Research publishes articles featuring novel, basic cancer research discoveries that prioritize broad molecular and cellular processes. Areas of emphasis include cell cycle and ...

“It’s not random,” said Anthony Kossiakoff, a protein engineer at the University of Chicago who studies protein structure-function ... binding properties of a full antibody, which they called single ...

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Through study of a neutralizing monoclonal antibody termed mAb P-4G2, which neutralizes the zoonotic pathogen Puumala virus (PUUV), we provide a molecular-level basis ... This work provides a ...