Pittsburgh is a 3-point favorite in the latest Seahawks vs. Steelers odds from SportsLine consensus, while the over/under for total points scored is set at 40.5. The Steelers are -152 money line favorites (risk $152 to win $100),

The Seahawks backfield is suddenly changing. After Kenneth Walker taking majority of the snaps when healthy, it's now Zach Charbonnet taking command in 2025. In week one Walker had 40% of the snaps while Charbonnet commanded 58%. Now how should fantasy managers respond in week two?

Learn which TV channel or how to live stream the NFL Week 2 Pittsburgh Steelers and Seattle Seahawks game, Sunday, Sept. 14.

The noise and the 12s and the beautiful building aren't exactly teaming up to make Lumen a definitive advantage for the Seahawks, however. They were 3-6 at home last year and a gaudy 7-1 on the road. Over the last four seasons, they are only 13-14 at Lumen.

The Seahawks made two expected moves Saturday, elevating safety D’Anthony Bell and nose tackle Brandon Pili from the practice squad.

Nick Emmanwori is out, and Witherspoon is doubtful, so Seattle elevated D’Anthony Bell from the practice squad to add secondary depth.

"The Steelers are playing the home opener against a Seattle team that lost a tough one to the 49ers last week. Aaron Rodgers looked good against the Jets and I think that will carry over here. The Steelers will go to 2-0 as Rodgers plays well and DK Metcalf does some damage to his former team," Prisco wrote.

The Seattle Seahawks could face a challenge in the play of quarterback Sam Darnold, who struggled in a Week 1 loss.