NFL.com keeps you up to date with all of the latest injury updates ahead of Sunday's..

On Saturday, the San Francisco 49ers announced the following roster moves ahead of Sunday's matchup against the New Orleans ...

With Brock Purdy sidelined, the 49ers must stick to three key principles to secure a road victory against the Saints in their ...

The San Francisco 49ers will take on the New Orleans Saints this weekend. Here's what the experts think will happen on Sunday ...

Watch Matt Maiocco’s full interview with Kyle Shanahan on “49ers Game Plan,” airing at 10:30 p.m. PT Friday on NBC ...

When the 49ers made a trade to acquire the third overall pick in the 2021 draft, everyone expected them to take a quarterback ...

The 49ers won't have Brock Purdy for Sunday's game against the Saints and they didn't sign a quarterback to the 53-man roster ...

The San Francisco 49ers roster moves ahead of Week 2 didn't include the addition of a practice squad WR, which may be good news for an ...

San Francisco 49ers offensive tackle Trent Williams is questionable for Sunday's game against the New Orleans Saints. Kyle Shanahan has a ...

The 49ers Faithful are on the move for a second consecutive week.After traveling to the Pacific Northwest to see a 17-13 win over the Seattle Seahawks in ...

The San Francisco 49ers and New Orleans Saints will meet on Sunday. Here's what fantasy owners should do with their 49ers in ...

The 49ers enter Sunday's game in New Orleans seeking to open a season with back-to-back road wins like in 2019, '21 ...