We identified two biomarkers and a potential therapeutic agent for AAA, thus enhancing understanding of the molecular mechanisms underlying the disease and offering novel strategies for its clinical ...

Pulmonary fibrosis (PF) is a progressive interstitial lung disease characterized by excessive extracellular matrix deposition and tissue scarring, and leading to impaired lung function and respiratory ...

Objective: The goal of this study was to examine the prognostic performance of optical flow ratio (OFR) among patients with coronary artery disease (CAD) after percutaneous coronary intervention (PCI) ...

Silver nanoclusters (AgNCs) have emerged as highly adaptable nanomaterials with vast potential in theranostic applications, by integrating therapeutic and diagnostic capabilities within a single ...

Coronary heart disease (CHD), the most common cause of mortality globally, poses a formidable challenge to modern healthcare systems. Artificial intelligence (AI) is playing an increasingly important ...

Phosphodiesterase-4 (PDE4), a member of the phosphodiesterase superfamily, has highly important roles in cyclic nucleotide signaling pathways and a variety of skin disorders. Blocking PDE4 activity ...

Diabetic cardiomyopathy (DCM), an independent diabetes complication, is characterized by abnormalities in myocardial structure, function, and metabolism, including diminished myocardial contractility, ...

Cardiovascular disease remains a leading cause of death and disability worldwide. Heart failure (HF) is the end stage of various cardiovascular diseases. Despite recent advancements in understanding ...

Background: Although 2-methylbutyrylcarnitine (2MBC) has been associated with metabolic disorders and promotes thrombosis, its effect on atherosclerosis remains elusive. This study was aimed at ...

Background: Fenofibrate (FF) is a BCS class II compound whose poor solubility poses challenges in drug delivery and bioavailability. Solid self-micro emulsifying drug delivery systems (S-SMEDDS) have ...

Heart failure (HF) is a clinical syndrome with a wide variety of clinical presentations, pathophysiologies, and natural histories. HF is becoming more prevalent globally, thus increasing effects on ...

Asteroid and comet impacts can produce a wide range of effects, varying from large crater-forming events to high-altitude, non-destructive airbursts. Numerous studies have used computer hydrocode to ...