UroToday4d
Investigating the prognostic utility of GSTP1 promoter methylation in prostate cancer.
We aim to determine the prognostic significance of glutathione S-transferase Pi 1 DNA methylation (mGSTP1) in two independent prostate cancer cohorts with long-term clinical follow-up data. We first ...
UroToday4d
Selective treatment de-escalation in advanced prostate cancer: have we come full circle?
Compelling evidence has solidified the notion of early treatment intensification in managing patients with metastatic hormone-sensitive prostate cancer (mHSPC). Landmark trials have provided Level 1 ...
UroToday4d
Predicting Response to Bipolar Androgen Therapy (BAT) - A Blood-Based Biomarker Approach
Alicia Morgans interviews Samuel Denmeade about the TRANSFORMER trial and Bipolar Androgen Therapy (BAT) for prostate cancer. Dr. Denmeade explains that the trial, involving 200 patients, compared ...
UroToday4d
Differential expression of metabolic enzymes in testicular germ cell tumors: The impact of glycolytic metabolism in embryonal carcinoma histotype.
Testicular germ cell tumors are the most common solid malignancies in young men, with increasing incidence worldwide. Broadly classified into seminomas and non-seminomas, they exhibit distinct ...
UroToday4d
The effect of tumor downsizing on surgical complexity during nephrectomy after immune checkpoint inhibitors for metastatic renal cell carcinoma.
Immune Checkpoints Inhibitors (ICI) have changed the therapeutic landscape of metastatic renal cell carcinoma first-line treatment with complete response (CR) at metastatic sites observed in 10 to 15% ...
UroToday4d
Incidence and Survival of Patients With Prostate Cancer in North-Rhine Westphalia, Germany.
There is no organized prostate cancer screening in Germany. The aim of this study was to investigate the development of incidence and survival in patients with primary malignant tumors of the prostate ...
UroToday7d
Antibiotic therapy for treating overactive bladder is not supported by clinical evidence.
A number of reports have suggested that the use of prolonged antibiotic treatment could be an effective therapy for patients with overactive bladder (OAB); however, this approach is contrary to ...
UroToday11d
Managing Small Renal Masses in Renal Cell Carcinoma Videos
Results from the Phase 3 Study of 89Zr-DFO-Girentuximab for PET/CT Imaging of Clear Cell Renal Cell Carcinoma (ZIRCON) - Brian Shuch ...
UroToday7d
The Association Between Anthropometric Indices and Overactive Bladder (OAB): A Cross-Sectional Study From the NHANES 2005-2018.
The association between different anthropometric indices, including body mass index (BMI), a body shape index (ABSI), lipid accumulation product (LAP), visceral adiposity index (VAI), waist ...
UroToday11h
AUA Guidelines 2020: Benign Prostatic Hyperplasia
(UroToday.com) As part of the American Urological Association 2020 Virtual Annual Meeting’s AUA guidelines update, Steven Kaplan, MD, from Mount Sinai Medical Center provided updates to the benign ...
UroToday7d
Risk factors, urodynamic characteristics, and distress associated with nocturnal enuresis in overactive bladder -wet women.
Patients with overactive bladder syndrome-wet (OAB-wet) experience urgency urinary incontinence, particularly urinary frequency and nocturia. Nocturnal enuresis (NE) is less addressed among OAB-wet ...
UroToday7d
Risk Factors and Contemporary Management Options for Pain and Discomfort Experienced During a Prostate Biopsy - Beyond the Abstract
Advances in imaging interpretation have led to more accurate risk stratification for men being diagnosed with prostate cancer (PCa). A significant number of men are diagnosed with low-risk prostate ...