USC forced three turnovers and unleashed a potent run game, rolling to a 33-17 win over Purdue in West Lafayette, Ind., Saturday.

The Purdue Boilermakers had their opportunities to grab a big time victory early in the 2025 season against the USC Trojans but just couldn’t make the plays necessary when needed. Although the offense moved the ball up and down the field all night,

USC is 2-0 against the spread to start the season and has covered the spread with ease, including a 35.5 line in Week 1. Purdue is 1-1 ATS and about to face the Big Ten's most potent offense, which is averaging 676 yards per game. The SportsLine model projects the Trojans will cover the spread in 65% of simulations.

USC football won its Big Ten road opener in 2025 against Purdue. The Trojans were never in danger of losing, but it was still a bumpy ride:

Make no mistake, Purdue fans didn’t expect to win this game. Did they think there was a chance? Sure, but expect to win it? No. Just look at the fan survey results from this week. Just 25% of you all thought that Purdue would take down the Trojans.

USC football will travel to West Lafayette to face off against the Purdue Boilermakers for their Big Ten opener. The Trojans, like they were in their dominating

The first meeting between the Trojans and Boilermakers since 1998 is delayed due to lightning. It is taking place at Ross-Ade Stadium in West Lafayette, Indiana. The game was scheduled to kick off at 3:40 p.m. ET.