Mar 6, 2024 · There are four laboratory tests used to diagnose Clostridioides difficile infection or CDI.

Rarely, to help confirm a diagnosis of C. difficile infection, a health care provider might check the inside of the colon. Tests used are either flexible sigmoidoscopy or colonoscopy.

Clostridioides difficile, or C. diff, is a highly contagious bacterium that causes diarrhea and colitis. It often infects people who’ve recently taken antibiotics.

The currently available tests for CDI, particularly the molecular tests (C diff PCR and GI Panel) are highly sensitive and may detect levels of the bacteria which are not clinically meaningful.

C. diff testing checks a sample of your stool (poop) for signs of an infection with a bacteria called C. diff. C. diff is also called C. difficile or Clostridioides difficile.

Toxigenic culture (TC), formerly the gold standard test, involves the culturing of C. difficile from stool; cytotoxic assays are then used to test isolates for cytotoxin production.

Sep 30, 2025 · The test is done to see if diarrhea that won't go away was caused by Clostridioides difficile (C. diff) toxins.

You can also click here to read the full guide on C. diff testing. It explains each test in plain English, shows how to interpret different result combos, and helps you make sense of your …

Patients currently admitted to an inpatient service who develop symptoms suspicious of C. difficile infection should be screened for diagnosis and testing as per Figure 1.

Positive culture only means C. diff present, not necessarily that it is causing disease Testing Algorithm For patients with suspected Clostridium difficile associated diarrhea (CDAD) Low …