ATCC offers a variety of products for fibroblast culture, including normal human dermal fibroblasts (NHDF), media, and growth kits to support either low-serum or serum-free cell growth. To improve your clinically relevant respiratory research, we offer primary fibroblast primary cells from COPD, asthma, fibrosis, and cystic fibrosis.

Fibroblasts are diverse mesenchymal cells that participate in tissue homeostasis and disease by producing complex extracellular matrix and creating signaling niches through biophysical and biochemical cues.

BJ cells are fibroblasts established from skin taken from normal foreskin from a neonatal male. Applications include toxicology research.

May 22, 2023 · Human fibroblast cell lines provide valuable insights into the complex interplay of cellular processes, signaling pathways, and the extracellular matrix in health and disease. They can also be genetically manipulated, such as through CRISPR/Cas9 technology, to study the function of specific genes or pathways in the context of fibroblast biology.

Primary Dermal Fibroblast; Normal, Human, Adult (HDFa) is a skin cell line with research applications in responding to pathogens, skin aging, wound healing, gene delivery, and skin diseases, including scleroderma.

A fibroblast cell line, which has been used in rabbit models (Lee et al., 2001; Madry et al., 2010) and primary synovial fibroblasts, which have already reached human experimentation (Evans et al., 2005; Wehling et al., 2009), have been transfected with genes encoding soluble factors (e.g. IL-1Ra (Oligino et al., 1999; Watson et al., 2013; Kay ...

Jan 10, 2022 · In this article in a series of cell culture articles, we describe five reasons why fibroblasts are commonly used in cell culture; exploring their properties and functions and how this translates to their widespread use in cell culture studies.

Fibroblasts are diverse mesenchymal cells that participate in tissue homeostasis and disease by producing complex extracellular matrix and creating signaling niches through biophysical and biochemical cues.

Apr 17, 2023 · Some commonly used human fibroblast cell lines include: BJ cell line: The BJ cell line is derived from normal human foreskin fibroblasts. It is a diploid cell line, meaning it retains the normal human chromosome number, and is widely …

Mouse Embryonic Fibroblasts (MEFs) are a type of fibroblast prepared from mouse embryo. MEFs show a spindle shape when cultured in vitro, a typical feature of fibroblasts. The MEF is a limited cell line. After several transmissions, MEFs will senesce and finally die off.