Guidelines for in vivo mouse models of myocardial infarction
Dec 1, 2021 · Despite significant improvements in reperfusion strategies, acute coronary syndromes all too often culminate in a myocardial infarction (MI). The consequent MI can, in …
Modeling Myocardial Infarction in Mice: Methodology, …
Abstract. Myocardial infarction is one of the most serious and widespread diseases in the world. In this work, a minimally invasive method for simulating myocardial infarction in mice is described …
Mouse models of myocardial infarction: comparing permanent ligation …
Nov 18, 2020 · Mice are more tolerant of myocardial injury than humans. Infarct sizes of <30% are well tolerated in mice, and their hearts retain sufficient contractile function to prevent …
Novel Mouse Model of Myocardial Infarction, Plaque Rupture, …
Jun 17, 2024 · We characterized a novel mouse model with a C-terminal mutation in the scavenger receptor class B, type 1 (SR-BI), combined with Ldlr knockout (designated SR-BI …
Myocardial Infarction in Neonatal Mice, A Model of Cardiac …
Myocardial infarction induced by coronary artery ligation has been used in many animal models as a tool to study the mechanisms of cardiac repair and regeneration, and to define new targets …
A Minimal-Invasive Approach for Standardized Induction of Myocardial …
For optimal standardization, we first evaluate the left anterior descending artery (LAD) by high frequency (HF) ultrasound. In B-mode imaging of anesthetized mice, the LAD is scanned from …
Mouse models of myocardial infarction: comparing permanent …
Nov 18, 2020 · Myocardial infarction (MI) is a disease of major consequence in the modern world, causing permanent, irreversible damage to the heart. Survivors are at risk for developing …
Reprogramming the myocardial infarction microenvironment …
Aug 6, 2024 · Myocardial infarction (MI) has a 5-year mortality rate of more than 50% due to the lack of effective treatments. Interactions between cardiomyocytes and the MI …
Myocardial infarction augments sleep to limit cardiac ... - Nature
Oct 30, 2024 · Here we report that in humans and mice, monocytes are actively recruited to the brain after myocardial infarction (MI) to augment sleep, which suppresses sympathetic outflow …
Targeted Treatment of Myocardial Infarction by Macrophage …
To investigate the therapeutic effects of MM/RESNPs, myocardial infarction was induced in mice, which were then grouped and treated with tail vein injections of saline, RES, RESNPs, and …